Wednesday, June 13, 2012

Die-Off Syndrome: The Herxheimer Response

As explained in detail in the book Breaking the Vicious Cycle: Intestinal Health Through Diet, the intestines of people with gastrointestinal issues, such as inflammatory bowel disease, Crohn's, celiac disease, and ulcerative colitis, are overgrown with bacteria and yeast. These organisms typically live in the large intestine, but given the right conditions, they overpopulate the large intestine and migrate to the small intestine and, in severe cases, the stomach. (Please see the book for a more detailed description of this process.)

All of these bacteria are eating the starchy, sugary foods your damaged intestines can't digest, releasing waste products and toxins that further damage your intestines. The bacteria contain toxins in their cell walls that are released when they die. These toxins make you sick. When many bacteria die at once, they all release toxins at the same time. Taking antibiotics or antifungal medication can cause die-off, as can changing your diet to eliminate the foods these bacteria eat, effectively starving them.

Symptoms of Die-Off Syndrome

Remember that die-off symptoms are temporary. Even though you may feel miserable, keep in mind that these symptoms are a sign of all the bad bacteria that were causing problems in your digestive tract. The worse you feel, the greater the number bacteria in your intestines, robbing you of vital nutrients.

Possible symptoms can include headaches, irritability, dizziness, aching joints, back pain, rash, and sleep disturbances. You may also experience cold symptoms, such as a runny nose or cough, and flu-like symptoms, such as fever, nausea, vomiting, and abnormal bowel movements (diarrhea/constipation). Extreme hunger and cravings for sugary, starchy carbohydrates are also common symptoms; as the bacteria and yeast die, they send you messages to eat the food that will save them.

Not everyone experiences die-off symptoms, and those who do experience them to varying degrees.

How to Ease the Symptoms

Avoid these symptoms as much as possible by gradually reducing SCD illegal foods before starting the intro diet. Give yourself at least a week to eliminate these foods before starting the intro diet. Make sure to drink plenty of filtered water before and during the intro diet; staying hydrated will help your body flush the toxins out faster. Taking antibiotics or antifungal medication during or immediately before starting the intro diet may make symptoms worse.

Achy joints, back pain, and other symptoms may be eased by soaking in a warm Epsom Salt bath. Chicken soup, a key part of the intro diet, has natural anti-inflammatory properties, as do other bone broths. Be sure any soup or broth is completely SCD legal. Get plenty of rest and drink lots of water. If you're able, start the intro diet when you have a few free days, and temporarily shelve all other responsibilities until you know how your body will react.

Who is Herxheimer, Anyway?

Karl Herxheimer was a German dermatologist. He and Adolf Jarisch, an Austrian dermatologist, are credited with the discovery of the Herxheimer response, also called the Jarisch-Herxheimer reaction and die-off syndrome. This phenomenon was first observed during the treatment of syphilis with antibiotics.


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